Some men and women experience immediate side effects of testosterone treatment, such as acne, disturbed breathing while sleeping, breast swelling or tenderness, or swelling in the ankles. However, the wisdom and effectiveness of testosterone treatment to improve sexual function or cognitive function among postmenopausal women is unclear. Also, as men get older, their livers make more sex hormone binding globulin (SHBG), which binds to testosterone circulating in the bloodstream. Women with high testosterone levels, due to either disease or drug use, may experience a decrease in breast size and deepening of the voice, in addition to many of the problems men may have. Part of this may be due to the difficulty defining "normal" testosterone levels and "normal" behavior. It's one of several androgens (male sex hormones) in females. Only free testosterone and some of the testosterone that is loosely bound to albumin are biologically active, he says. Less straightforward is exactly what level of testosterone is low enough for a clinician to diagnose and treat low testosterone. "A big misconception I see is that taking testosterone is always the answer, because that’s really not the case," Dr. Debaja says. "I don't think people are well informed of risks," says Turchin. Don't have any symptoms at all, And an increased risk of heart And blood pools in the atria. When this happens, blood doesn't Causing it to beat abnormally. The testes, unlike the ovaries, do not run out of the substance it needs to make testosterone. Stay on top of latest health news from Harvard Medical School. Sign up for HEALTHBeat and receive trusted health information delivered right to your inbox. Get the latest in health news delivered to your inbox! Typically, it drops by about 1% per year after age 30. Once girls start having a period each month, their bodies begin to release testosterone from their ovaries. Testosterone directs the formation of sperm and controls your ability to have and maintain an erection — so it has quite a role to play when it comes to male fertility. In utero, testosterone is responsible for the development of your penis and testes if you have them. In babies with ovaries, these organs make testosterone. While testosterone therapy can be an option, it has disadvantages as well. Testosterone levels naturally decline as you age. If you are not in menopause, your estrogen levels should range from 30 to 400 picograms per milliliter. In women, especially those who haven’t yet gone through menopause, the most common cause of excess testosterone is PCOS. Estrogen levels also rise during a healthy pregnancy.